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Most deaths from childbirth, malaria, tuberculosis, malnutrition and cholera can be prevented with care that already exists and costs little. This page covers where that care works best, why reaching people is the hard part, the gaps that exist in wealthy countries too, and the well-meant help that backfires. Every health cause on our list is shown at the end, with the partner that carries it out.

By Global Relief Group · Last updated:

35
Verified causes
26
Countries
35
Partner organizations

The medicines and methods that prevent most deaths in poor countries are not new or expensive. A trained midwife, a treated bed net, a sachet of therapeutic food or a few litres of rehydration solution can decide whether someone lives. What is usually missing is getting that care to the people who need it, and keeping it there.

Six problems that cheap, proven care can solve

The latest global figures, the care with the strongest evidence behind it, and where the causes we list fit in:

The problemWhat worksCauses we list
Dying in childbirth
About 260,000 women died from pregnancy or childbirth in 2023, more than 700 a day; about 70% of these deaths were in sub-Saharan Africa (WHO, 2025)
Skilled birth attendants and midwives, with supplies and a way to refer emergenciesMidwives in Afghanistan (Maternal Mortality Reduction Fund) and South Sudan; antenatal and postnatal care in Papua New Guinea
Malaria
282 million cases and 610,000 deaths in 2024; about 95% of deaths were in Africa, mostly young children (World Malaria Report 2025)
Insecticide-treated nets cut child deaths from all causes by about 17% where malaria is common (Cochrane, 2018)Nets in Sudan; indoor spraying and rapid tests in Djibouti
Tuberculosis
10.7 million people fell ill and 1.23 million died in 2024, more than from any other single infection (WHO, 2025)
Finding cases early and helping patients finish months of treatmentCommunity treatment in India (TB Treatment Access Fund), mobile X-ray screening in Nigeria, TB and HIV care in South Africa, island care in Indonesia
Child malnutrition
42.8 million children under five were too thin for their height (wasted) in 2024, 12.2 million of them severely (UNICEF, WHO and World Bank, 2025)
Most children without complications can be treated at home with ready-to-use therapeutic food (WHO, 2023)Screening and treatment in Yemen, Somalia and Ethiopia
Cholera
451,499 cases and 7,870 deaths in 47 countries in 2025, the most deaths reported since 1999 (WHO, 2026)
Prompt rehydration keeps deaths below 1% of cases, WHO’s benchmark; chlorination stops the spreadRehydration points and chlorination in Haiti and Yemen
Too few health workers
WHO projects a shortfall of 11.1 million health workers by 2030, mostly in low- and lower-middle-income countries
Trained, supervised and paid community health workers (WHO guideline, 2018)Community health workers in Malawi, rural health posts in Mali, clinics in Uganda’s refugee settlements
Figures are the latest global estimates from the organizations named.

How much does it cost to save a life? GiveWell, which evaluates charities, estimated in 2024 that its top-rated programmes save a life for roughly US$3,000 to US$5,500 each, with seasonal malaria medicine for children in Nigeria near the lower end. Few programmes reach that standard of evidence, but it is a useful benchmark: an appeal that claims to save a life for a few dollars is not being straight with you.

Why reaching people is the hard part

Distance. In rural Malawi, the community health workers funded through the Community Health Worker Programme serve villages more than a day’s walk from the nearest clinic. A trained local worker who can test for malaria, spot pneumonia and refer a difficult pregnancy brings the health system to the village rather than waiting for the village to reach it.

Cost. Charging for care keeps the poorest away and pushes others into debt. The World Health Organization and World Bank estimate that 1.6 billion people were living in poverty or pushed further into it by health spending in 2022, and 2.1 billion faced financial hardship from health costs. That is why several causes fund free or subsidized care, such as the Primary Care Access Fund, which pays for consultations and medicines at community health centres for households that can no longer afford them.

Empty shelves. A clinic without medicines does not help much. Even in a middle-income country with a large public health system, a 2024 survey of 9,831 primary health centres in Indonesia found that only 42% of mental health medicines were available, against 82% for the most important general medicines. Funding for supplies, such as the Rural Health Post Supply Fund, keeps existing health posts able to treat people.

War. Where fighting has broken the health system, care has to move. In Sudan, the Conflict Zone Field Hospitals fund keeps mobile surgical units supplied with fuel, consumables and staff; in the Central African Republic, other funds repair and staff clinics in areas recovering from conflict.

Health care gaps in wealthy countries

Rich countries rarely lack medicines. Their gaps are waiting times, distance and groups the system does not reach. The causes we list address problems like these:

  • United Kingdom: the NHS waiting list in England stood at about 7.3 million cases in 2026 (NHS England), and hundreds of thousands of children and young people were waiting for NHS mental health support. Causes fund patient advice, interim counselling for young people, and peer advocates who help people experiencing homelessness reach care.
  • Canada: the median wait from a GP referral to specialist treatment was 28.6 weeks in 2025 (Fraser Institute). The Specialist Care Access Fund pays travel and accommodation for patients whose treatment is far from home.
  • United States: rural counties that have lost their only hospital rely on video consultations with distant specialists, which the Rural Telehealth Network helps equip.
  • Sweden, Spain and Australia: telepsychiatry in Sweden’s sparsely populated north, mobile health units in depopulated parts of Castilla y León, and free or low-cost mental health support for young people in regional Australia.
  • Germany: people with rare conditions in Europe wait nearly five years on average for a correct diagnosis (EURORDIS); the Rare Disease Research Trust funds counselling that helps them reach the right specialist centre.

Well-meant help that backfires

Shipping medicines or flying in volunteer doctors feels like the most direct way to help. The evidence says to be careful.

Donated medicines. The World Health Organization’s guidelines on medicine donations say donations should be based on a need the recipient has expressed, should be medicines approved and on the country’s essential list, should arrive with at least a year before they expire, and should meet the same quality standard as in the donor country: “If the quality of an item is unacceptable in the donor country, it is also unacceptable as a donation.” The guidelines exist because of experience. In an analysis of 56 tonnes of medicines sent to Sri Lanka after the 2004 tsunami, only 10% matched what had been requested, and half had no expiry date (WHO, 2010). During the war in Bosnia and Herzegovina in the 1990s, a study funded by Médecins Sans Frontières estimated that about 17,000 tonnes of donated medical supplies, roughly half of everything sent between 1992 and 1996, were inappropriate.

Short medical trips. Two systematic reviews of short-term medical missions, published in 2015 and 2017, found that evidence on their results was sparse and the activity largely unregulated. Most of the recommended practices they found came back to one point: link the mission to the local health system, so patients have follow-up care after the visitors leave.

That is why the health causes we list mostly fund local staff and work inside the national health system, rather than shipping donated goods or sending volunteer trips.

Questions to ask a health charity

  • Does it work with the national health system? Good programmes coordinate with the ministry of health or district health office and follow national treatment protocols, rather than running a parallel system that disappears when funding ends.
  • Does it use treatments WHO recommends? Treated nets, oral rehydration, outpatient therapeutic food, and trained, supervised health workers and midwives all have strong evidence behind them.
  • What results does it report? Look for outcomes, not just activities: recovery rates in malnutrition programmes (humanitarian standards aim for more than 75% recovered and fewer than 10% deaths), deaths in cholera units, or births with a skilled attendant.
  • Who runs it when the money stops? Programmes that train and pay local staff, and plan with local authorities, leave something behind.

The partner details on each cause page, including registration, founding year and track record, help with the first question. Our vetting process explains what we confirm before listing a cause.

Every Health & Medical Aid cause we list

Each cause names the partner organization that carries out the work and when our team last verified it. Open a cause for full details, or donate directly.

Canada

Specialist Care Access Fund

Subsidizes travel and accommodation for patients facing Canada's median 28.6-week wait from GP referral to specialist treatment, roughly triple the wait in 1993, when that care is far from home.

Funds handled by Hope Air · verified Sep 2022

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Djibouti

Malaria Prevention Program

Funds indoor residual spraying and rapid diagnostic test kits in one of the six countries carrying the bulk of regional malaria transmission.

Funds handled by Programme National de Lutte contre le Paludisme (Ministry of Health, Djibouti) · verified Feb 2025

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Germany

Rare Disease Research Trust

Funds counselling and diagnostic guidance for people with rare conditions, who in Europe wait nearly five years on average for a correct diagnosis, helping them reach the right specialist centers.

Funds handled by ACHSE e.V. (Allianz Chronischer Seltener Erkrankungen) · verified Jun 2023

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Haiti

Cholera Response Fund

Funds oral rehydration points and chlorination supplies during active cholera outbreaks in displacement settlements with no reliable clean water.

Funds handled by Zanmi Lasante (Partners In Health Haiti) · verified Mar 2025

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India

TB Treatment Access Fund

Funds community-based TB treatment points and adherence support for patients who can't afford to miss work, in India, which accounts for roughly 25% of global TB cases, more than any other country.

Funds handled by Operation ASHA · verified Nov 2022

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Portugal

Mental Health Access Network

Funds psychological support, group programs and family sessions for people with mental illness, in a country where public psychological care is thin and waits for therapy can last months.

Funds handled by ENCONTRAR+SE (Associação para a Promoção da Saúde Mental) · verified May 2023

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Sudan

Conflict Zone Field Hospitals

Keeps mobile surgical units running in areas where the formal health system has collapsed under the ongoing civil war — funding covers fuel, medical consumables, and staff stipends.

Funds handled by Médecins Sans Frontières (MSF) Sudan · verified Apr 2022

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United States

Rural Telehealth Network

Funds video-consultation equipment for rural clinics in counties that have lost their only hospital in the past decade, connecting patients to specialists hours away.

Funds handled by HRSA Federal Office of Rural Health Policy (Telehealth Network Grant Program) · verified May 2024

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Yemen

Malnutrition Screening Program

Funds community-based screening for acute malnutrition in children, catching cases early enough for outpatient treatment rather than hospitalization.

Funds handled by Action Against Hunger (Action Contre la Faim) Yemen · verified Apr 2026

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Common questions

Does my crypto go straight to the hospital or clinic?

No. Your crypto goes to Global Relief Group’s verified wallet, and the funds for that cause are passed to its partner organization as a grant, typically by bank transfer. Partners never need a crypto wallet.

Can I send medicines or medical supplies instead?

We don’t accept goods. Money lets local teams buy medicines that are approved in the country, labelled in a language staff understand and within date, which is what the World Health Organization’s donation guidelines ask for.

Which health causes help children most?

Malaria prevention, malnutrition treatment and safe-birth programmes mostly benefit young children and mothers. Most malaria deaths in Africa are children under five.

Can I give to health work in a specific country?

Yes. Each cause names its country. You can also browse all causes in a country through our country giving guides.

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